Called the Revival World Tour, the string of 75 concerts will be hitting cities such as Brooklyn, London, Paris and Milan over the next few months.
But Selena only had one chance to start things off with a bang - and she did just that when she sang in Sin City.
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She'd also brought along with her a sparkling catsuit, which seemed to pump her with confidence as she worked her magic with the microphone.
On more than one occasion the brunette beauty was spotted throwing some sexy shapes and showing off her killer body.
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However on that occasion the singer had to cancel a string of shows, citing a need to 'spend time on myself' as the reason.
According to The Hollywood Reporter, Selena will be donating proceeds from each ticket sold for her new tour to Alliance for Lupus Research.
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"It's the music that I created. It's the music that I wrote. That is my story to a T," she said in a video posted on Instagram.
"I'm incredibly nervous but I think the past few rehearsal days there's been a really huge part that's missing to the show. And I know that that's the fans.
"So at this point I'm nervous but I'm eager and I'm excited that they're going to bring me to life. That's the biggest part that's missing."
Earlier this week there was evidence of her continued popularity when she surpassed Kendall Jenner for the most-liked picture on Instagram.
The image - actually posted by Justin Bieber- featured Selena in a lip lock with her ex-boyfriend.
Even though it was only posted in March it's already on its way to racking up four million 'likes' on the social media platform.