"The filming company informed us they have cancelled filming on Monday," spokesperson Chief Superintendent Wayne Minnaar said.
Albetina Sisulu street (previously Market) would no longer be blocked off between Harrison and Rissik streets from 07:00 until 19:00 as said earlier.
Minnaar said filming in the street would begin on Tuesday at 18:00 until Wednesday morning.
Other streets affected from 14 to 23 February would be President street between Rissik and Eloff streets and Joubert street between Harrison and Rissik streets, he said.
Parts of Commissioner, Sauer, and Albetina Sisulu streets would also be closed.
Motorist were urged to use Jeppe, Bree, Pritchard, Marshall, and Anderson streets as alternatives.
Minnaar said Kingsley Sithole road and Basil Zuma street in Orlando East would be closed to traffic on Thursday.
"The public is requested to exercise patience and use alternative roads in the meantime."
The sequel, titled Avengers: Age of Ultron, will feature well-known actors Robert Downey Jr, Scarlett Johansson, Chris Evans, and Chris Hemsworth as popular superheroes.